Mapped Drives: Unable to load Clr instance error V8
After an update, customers with mapped drives may have issues accessing their RMA through their workstation even after running a network client install. The following is one of the errors they may receive after an update:

The cause, and what to do when this occurs will be explained below.
CauseWhen the wwDotnetBridge.dll file is shared through a mapped drive, .NET treats the network loaded DLL as coming from a different low rights Windows Security Zone which - by default - is then not allowed to execute.
Resolution
You will need to create a new file in the root directory of RMA named RMA.exe.config. You will enter the following within this file:
<configuration><runtime><loadFromRemoteSources enabled="true"/></runtime>
</configuration>
Remember, the path to this file should be along the lines of "C:\RMA\RMA.exe.config".
Once you have made this addition, you should be able to use RMA through the mapped drives without any issues.
More Information
For more descriptive information regarding this issue, you can visit Unable to load CLR Instance Error - West Wind Client Tools (west-wind.com)